Eplerenone, amlodipine and experimental hypertension: one plus one equals three

Meiotic Spindle Self-Organization: One Plus One Equals Only One

Like other cellular organelles, the bipolar spindle is a structure of well-defined size and shape. Now, spindle fusion experiments using micro-manipulation have allowed current models for spindle morphogenesis and size control to be tested.

One sequence plus one mutation equals two folds.

I n this issue of PNAS, Alexander et al. (1) report an observation that will be a topic of heated discussion among biochemists for a long time to come. A single amino acid substitution can, in the right context, completely change the fold of a protein. And the structural change produced by this one mutation cannot be dismissed as a semantic issue over what constitutes a different fold. As shown...

Physiological coreceptor use by dual-tropic HIV-1: one plus one equals one.

One plus one equals three (or more …): combining the assessment of movement behavior and subjective states in everyday life

Movement behavior, i.e., the overt permanence of postures andmotions in daily life, is of crucial importance in human functioning. Movement behavior contributes to participating in daily life, and improves quality of life (Buffart et al., 2009). In addition, movement behavior—mostly described in terms of levels of physical activity, active lifestyle, and/or sedentary lifestyle—has shown to be r...

In the Gut’s Microbial Community, One Plus One Equals Many (Effects)

December 2006 | Volume 4 | Issue 12 | e418 Most governments around the world set conservation policy based on the assumption that resource exploitation and species protection can co-exist in the same place. These policies have led to Orwellian “marine protected areas” that host commercial fi shing operations, leading one to wonder who’s protecting whom. A new study reveals the danger of this ap...